Unit on Cell Specification and Differentiation
Farrell Lab @ NICHD

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Lab News
Era: Recent - 2022 - 2021 - 2020 - Older

2021:

Christmas Potluck!

December 20, 2021

The Farrell and Rogers labs gathered to celebrate the holidays with a potluck, appropriately socially distanced outdoors.

Farrell and Rogers Labs Christmas Potluck

Lab Move-in Day

December 9, 2021

The renovations of our lab’s permanent space have finally finished, and we’ve just moved in! Looking forward to finishing setting up the lab, but especially to all being together.

Farrell Lab in New Lab Space

Birthday celebration for Paulina

November 24, 2021

The Farrell and Rogers labs gathered to celebrate Paulina’s birthday!

Farrell and Rogers lab

Lab Potluck

October 17, 2021

Thanks to Abhinav for hosting the lab for a potluck dinner!

Potluck at Abhinav's

Successful blastula transplants in the lab

August 5, 2021

Look at these two newly minted young embryologists!

Eric and Jeremy's transplant results

Lab Dinner

June 30, 2021

Finally the restrictions are beginning to lift, and the lab was able to gather for a real night out. Great company, as always. We are still looking forward to a full opening of the lab so that we can have as much fun during the day as well!

the Farrell Lab at dinner

March 10, 2021

Nature Biotechnology curated a collection of “25 landmark papers published across [their] history” as part of their 25th Anniversary Collection. One of Jeff’s co-first author papers from his post-doc, “Spatial reconstruction of single-cell gene expression data” was selected as one of these papers!

The project was an incredibly fun (and productive) collaboration, and Nature Biotechnology invited Rahul and Jeff to tell the personal story behind the manuscript, discussing the experience of working together, melding our fields, and finding our places in the field.

Additionally, you can read the paper here: Spatial reconstruction of single-cell gene expression data

Figure 1 from Spatial reconstruction of single-cell gene expression data; overview of the spatial assignment approach

Cheng-Yi Joins the Lab

February 15, 2021

Cheng-Yi Chen has joined the lab as a new post-doc! He received his PhD from the Stowers Institute, where he worked in the lab of Matt Gibson. He studied the anemone Nematostella vectensis and established that Nematostella primordial germ cells (PGCs) arise at the interface between hedgehog and patched expression domains in the developing mesentery, and that Hedgehog signaling is required for their specification. This supports the idea that the Nematostella PGCs are specified by inductive (zygotic) signals.

In the lab, he is focused on cells that undergo trans-specification during development and switch from one transcriptional program to another. He will investigate what causes cells to be trans-specified, follow them to determine their final fate and functionality, and investigate the mechanisms that enable this transcriptional transition.

Welcome, Cheng-Yi!

Portrait of Cheng-Yi Chen

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Recent - 2022 - 2021 - 2020 - Older